There are many sad facts antidepressants today. The list is long. I'll drop what I consider to be the saddest of sad that others are invited to add your own.
I stress the word "facts". In what I write about the results of scientific research. The results are not opinions, are the results. You may not experience in your neck, but it is not only disable.
I want to emphasize the motivation for maximum clarity, the word "today". I speak of the new antidepressants, particularly SSRIs, so dominate the market. I do not speak of tricyclic antidepressants or MAO inhibitors.
One last thing. With the publication of this post, I'm not sure the purpose of your antidepressants do not work for you. Perhaps they do. I'm not told to stop taking antidepressants. This decision is between you and your prescriber. What I seek the attention is a huge disproportion between the charm of SSRIs and their news. For this inequality, we thank Eli Lilly, Pfizer and others, and their young, cute, briefcase-full-of-drug-free sample REP armed servants.
The sad reality # 1 The antidepressants are not as effective today. A wonderful study of the reading is worthwhile in its entirety, the Freedom of Information Act for access to all of actual data provided by the original protocol of the FDA, whose effectiveness depends on a number of 'SSRI antidepressants (including profit Prozac, Paxil, Zoloft, Effexor, Celexa). The most important? A comprehensive approach 82% placebo rate of duplication. 82% of the overall effect of the drug was accompanied by a placebo, a chemically inert. The news is even worse for some drugs. overlap rate to 89% of Prozac - a fact painfully ironic, given the absurd outcry greeting the arrival of Prozac on market before the end of '80.
Sadly, # 2 The same study found no correlation dosage effects of drugs on mood. If people are on a higher being or a lower dose of the drug, it made no difference when it comes to feel less depressed. 20 mg was more useful, for example, 40 milligrams. This is particularly important because most doctors seem to think otherwise.
The sad reality, 3 # antidepressants are more effective, depending on the initial severity of depression. That finding comes from a study you can read here. It's a bit "complicated. What researchers found is that the relationship between initial severity and antidepressant medications can be attributed to increased drug efficacy, but reduce the effectiveness of a placebo. Placebo effect decreases steadily with increasing severity, trays and drug effectiveness falls too, but not placebo, as he always does. This is not the case that antidepressants are effective for depression worse, it's just that placebos are less effective.
The sad reality, 4 # This is somewhat unlike the sad reality # 3 In studies of the FDA, the efficacy of fluoxetine in the treatment of mild depression assessed. You do not exceed those given placebo.
Sadly # 5 We do not know why antidepressants work (if so). And the relationship Peter Kramer in "Listening to Prozac," the so-called model of biogenic amines in the atmosphere is, at best, "incomplete" and false at worst. Maybe that depression is something to do with serotonin, norepinephrine, or, but what exactly, and certainly difficult to say. It's one thing to know the effect of a drug is on brain chemistry, is quite another thing to know the mechanism of drug action. If you look at drugs like SSRIs in the office of a doctor on the mechanisms considered "unknown." It is a fundamental influence Amin antidepressant activity almost immediately, but not to lift the spirits (they do) after approximately 2 to 4 weeks. What happens in the brain during this 2 to 4 weeks? many theories about this, without a risposte.Raccontano historical facts.
I leave now. Saddest facts come to ...
Credit .... http://jalam1001.posterous.com/todays-antidepressants-some-sad-facts-psychol
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